September 19, 2022 —  A first-in-human (FIH) study using the ModulHeart device (Puzzle Medical Devices Inc.) has demonstrated significant improvement in cardiac output, left ventricular end diastolic pressure, and urine output in patients with heart failure or undergoing high-risk percutaneous coronary intervention (PCI). The findings were presented today during the 34th Transcatheter Cardiovascular Therapeutics (TCT) annual scientific symposium and simultaneously published in JSCAI, the official journal of the Society for Cardiovascular Angiography & Interventions (SCAI).