Zumbro Discovery is a biotechnology company founded by cardiologists, John Burnett MD and Horng Chen MD, that head up the Cardiorenal Research Laboratory at the Mayo Clinic. ZD100 is Zumbro’s lead drug candidate for the treatment of resistant hypertension (RH) which afflicts approximately 9 MM Americans and for which there is no FDA approved drug therapy. ZD100, which is a modified and patented version of the peptide released by the human heart to regulate blood pressure, has been shown to be safe and has demonstrated efficacy in treating RH patients in very early stage clinical trials. The company is currently pursing additional dose titration and toxicology studies for ZD100 in preparation for Phase II clinical efficacy trials.