The Massachusetts General Hospital (MGH), the Technical University of Munich (TUM), and Broadview Ventures, Inc. are collaborating on NIRF-IVUS Molecular Imaging of Atherosclerosis. The improved detection and stratification of high-risk plaques, i.e. atherosclerotic plaques at risk of causing heart attacks and strokes, is an unmet need. Early detection enables earlier intervention, prevention and tailored pharmacotherapy. Farouc Jaffer, MD, PhD, of MGH and Vasilis Ntziachristos, PhD of TUM, in conjunction with Intravascular Imaging Incorporated (“i3”) , are developing and testing prototype devices, software and systems for a comprehensive catheter-based approach to detect high-risk plaques in human arteries.