November 21, 2017
480 Biomedical develops new technology which imparts metal-like strength on bioresorbable polymers
WATERTOWN, Mass., Nov. 21, 2017 (GLOBE NEWSWIRE) — 480 Biomedical, a clinical-stage life science company committed to transforming the lives of patients with chronic diseases, announced a publication in Nature Materials highlighting the novel mechanical properties of the company’s fully bioresorbable polymeric implant technology.
As described in Nature Materials, the 480 Biomedical implant has been demonstrated in pre-clinical studies to possess resistive strength similar to metal, while maintaining flexibility and ultimately fully resorbing. This unique combination of attributes is achieved by combining a PLGA base structure with a proprietary bioresorbable elastomer, that is crosslinked via an innovative processing method. The elastomer is resistant to stress relaxation, allowing the implant to continually “spring-back”, thereby preventing migration or dislodgement after placement within the body. The structure is also highly flexible, and therefore conforms to the shape of irregular cavities, providing an ideal platform for efficient delivery of drugs directly to tissue. The study also demonstrates that the implant safely resorbs within the body.